Articular cartilage biology.

  title={Articular cartilage biology.},
  author={Michael Ulrich-Vinther and Michael D. Maloney and Edward M Schwarz and Randy N. Rosier and Regis J O'keefe},
  journal={The Journal of the American Academy of Orthopaedic Surgeons},
  volume={11 6},
Articular cartilage is a complex tissue maintained by chondrocytes, which undergo metabolic changes as a result of aging, disease, and injury. These changes may hinder tissue maintenance and repair, resulting in accelerated loss of articular surface and leading to end-stage arthritis. Researchers are investigating both normal and pathologic cellular and molecular processes as well as the development of chondroprotective agents to improve the metabolic function of articular cartilage. Current… CONTINUE READING