• Corpus ID: 43272490

ArticleOpen Access Journal of Parkinson ’ s disease & Alzheimer ’ s disease

@inproceedings{Foo2016ArticleOpenAJ,
  title={ArticleOpen Access Journal of Parkinson ’ s disease \& Alzheimer ’ s disease},
  author={Heidi Foo and Nagaendran Kandiah},
  year={2016}
}
demonstrated significantly more severe SVD-associated pathology compared to controls, which suggests that SVD may have a role in the pathophysiology of PD [12]. Another longitudinal study by Foo et al. demonstrated that progression of SVD was associated with significant cortical thinning in the frontoparietal regions with concomitant decline in memory, executive functions, and motor functions in PD patients [13]. This implies that the extent and progression of SVD could be associated with focal… 

Figures from this paper

References

SHOWING 1-10 OF 91 REFERENCES

Neuroimaging correlates of cognitive impairment and dementia in Parkinson's disease.

Progression of small vessel disease correlates with cortical thinning in Parkinson's disease.

Influence of White Matter Hyperintensities on the Cognition of Patients With Parkinson Disease

TLDR
It is confirmed that WMH might be associated with cognitive decline in patients with PD, regardless of age, sex, education status, duration or severity of PD symptoms, and vascular risk factors, and this result suggests that other nonvascular factors contribute to the progression of dementia in Patients with PD.

Brain atrophy and white matter hyperintensities in early Parkinson's disease

TLDR
It is concluded that global structural brain changes are not a major feature in patients with incident Parkinson's disease, and MRI volumetric measurements were not significant predictors of cognitive functions in PD patients.

Neuroimaging of brain changes associated with cognitive impairment in Parkinson's disease.

TLDR
Key findings involving structural MRI investigating grey and white matter changes, functional MRI to examine changes in neural activation and PET imaging to investigate metabolic and neurochemical changes that have led to an improved understanding of pathology associated with executive dysfunction in PD without dementia and PD-MCI are covered.

Cerebral microbleeds in patients with Parkinson’s disease

TLDR
Cerebral microbleeds occur more commonly in PD patients with dementia than in those without dementia, and the burden of CMBs may contribute to further cognitive impairment in PD.

White matter hyperintensities do not impact cognitive function in patients with newly diagnosed Parkinson's disease

Small‐vessel disease in patients with Parkinson's disease: A clinicopathological study

TLDR
The prevalence of vascular risk factors and SVD pathology was significantly lower in autopsy‐proven PD compared with controls living in the same community and the results of this study support the need for further research in this area.

Cerebral white matter hyperintensity in Parkinson's disease: a major risk factor for mild cognitive impairment.

Topography of cortical thinning associated with white matter hyperintensities in Parkinson's disease.

...