Article in press-uncorrected proof Minireview Measurement of the prohormone of brain type natriuretic peptide ( proBNP ) : methodological considerations and pathophysiological relevance

@inproceedings{Clerico2011ArticleIP,
  title={Article in press-uncorrected proof Minireview Measurement of the prohormone of brain type natriuretic peptide ( proBNP ) : methodological considerations and pathophysiological relevance},
  author={Aldo Clerico and Simona Vittorini and Claudio Passino},
  year={2011}
}
Recent studies demonstrated that large amounts of the prohormone peptide of brain natriuretic peptide (proBNP) can be detected in plasma of healthy subjects and in particular of patients with heart failure. As a result, a great part of B-type natriuretic peptides measured in patients with cardiovascular disease may be devoid of biological activity. These findings stimulated the set up of specific immunoassay methods for the measurement of the intact proBNP peptide. The aim of this review… CONTINUE READING
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