Arthritis and Pain. Neurogenic origin of joint pain

@article{McDougall2006ArthritisAP,
  title={Arthritis and Pain. Neurogenic origin of joint pain},
  author={Jason J McDougall},
  journal={Arthritis Research & Therapy},
  year={2006},
  volume={8},
  pages={220 - 220}
}
Arthritis pain affects millions of people worldwide yet we still have only a limited understanding of what makes our joints ache. This review examines the sensory innervation of diarthroidal joints and discusses the neurophysiological processes that lead to the generation of painful sensation. During inflammation, joint nerves become sensitized to mechanical stimuli through the actions of neuropeptides, eicosanoids, proteinase-activated receptors and ion channel ligands. The contribution of… CONTINUE READING

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Calcium channels as therapeutic targets in neuropathic pain.

The journal of pain : official journal of the American Pain Society • 2006

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