Arterial wall uptake of renal renin and blood pressure control.

@article{Loudon1983ArterialWU,
  title={Arterial wall uptake of renal renin and blood pressure control.},
  author={Michael F. Loudon and Robert L. Bing and Herbert F. Thurston and John Douglas Swales},
  journal={Hypertension},
  year={1983},
  volume={5 5},
  pages={
          629-34
        }
}
We have studied the contribution of circulating renin of renal origin to renin-like activity within the arterial wall and to blood pressure. Bolus injections of renin sufficient to elevate blood pressure by 44.7 mm Hg caused aortic renin to rise from 0.13 to 1.48 ng angiotensin I/100 mg/hr in nephrectomized rats. Elevation of aortic renin was still present at 6 hours, and this was associated with significant blood pressure elevation (p less than 0.05) which could be reversed by infusion of… CONTINUE READING

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