Arterial wall response to ex vivo exposure to oscillatory shear stress.

  title={Arterial wall response to ex vivo exposure to oscillatory shear stress.},
  author={Veronica Gambillara and Gabriela Montorzi and Christelle Haziza-Pigeon and Nikos Stergiopulos and Paolo Silacci},
  journal={Journal of vascular research},
  volume={42 6},
BACKGROUND The aim of this study was to analyze the arterial wall response to plaque-prone hemodynamic environments, known to occur mainly in areas of arterial trees such as bifurcations and branching points. In these areas, the vasculature is exposed to cyclically reversing flow that induces an endothelial dysfunction predisposing thus arteries to local development of atherosclerotic plaques. METHODS We used an ex vivo perfusion system that allows culturing arterial segments under different… CONTINUE READING

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