Arterial wall-determined risk factors to vascular diseases

  title={Arterial wall-determined risk factors to vascular diseases},
  author={Xing Li Wang and Jian Wang and Qiang Shi and Kendall D Carey and John L Vandeberg},
  journal={Cell Biochemistry and Biophysics},
Many decades of research have led to considerable in-depth understanding of circulating factors that may lead to coronary atherosclerosis. However, not every individual with serious known risk factors such as hypercholesterolemia or cigarette smoking develops atherosclerosis. Differential susceptibility of the arterial wall to circulating atherogenic risk factors, which may be largely controlled by genetic variants, may provide this missing link. Endothelial cells, the lining of the arterial… CONTINUE READING