Arterial stiffness and endothelial dysfunction independently and synergistically predict cardiovascular and renal outcome in patients with type 1 diabetes.

@article{Theilade2012ArterialSA,
  title={Arterial stiffness and endothelial dysfunction independently and synergistically predict cardiovascular and renal outcome in patients with type 1 diabetes.},
  author={Simone Theilade and Maria Lajer and Anders Jorsal and Lise Tarnow and H H Parving and Peter Rossing},
  journal={Diabetic medicine : a journal of the British Diabetic Association},
  year={2012},
  volume={29 8},
  pages={990-4}
}
AIMS To evaluate whether pulse pressure alone or with placental growth factor as estimates of arterial stiffness and endothelial dysfunction, predicts mortality, cardiovascular disease and progression to end-stage renal disease in patients with Type 1 diabetes. METHODS Prospective, observational study, median (range) follow-up 8 (0-13) years, 900 patients with Type 1 diabetes, 458 with diabetic nephropathy, mean ± SD age 44 ± 11 years. RESULTS During follow-up, we recorded 178 (20%) all… CONTINUE READING
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