Arterial sodium concentration in rats with hypertension induced by mestranol.

Abstract

Rats were made hypertensive by the oral ingestion of mestranol for 6 months. Carotid arteries from these hypertensive rats and from control rats were incubated in an extract of plasma from these rats, which contained 24Na and 14C-sucrose (an extracellular fluid marker). After sufficient time for equilibration, the vessels were removed and counted for 24Na… (More)

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