Arterial retention of apolipoprotein B(48)- and B(100)-containing lipoproteins in atherogenesis.

@article{Proctor2002ArterialRO,
  title={Arterial retention of apolipoprotein B(48)- and B(100)-containing lipoproteins in atherogenesis.},
  author={Spencer D. Proctor and Donna F. Vine and John Charles Mamo},
  journal={Current opinion in lipidology},
  year={2002},
  volume={13 5},
  pages={
          461-70
        }
}
PURPOSE OF REVIEW The "response to retention" hypothesis of atherosclerosis suggests that the arterial deposition of cholesterol is directly proportional to the concentration of circulating plasma lipoproteins. However, there is increasing evidence to support the concept that specific lipoproteins may be preferentially retained within the arterial wall, possibly as a result of greater affinity for cell surface and extracellular matrices. RECENT FINDINGS Recently, key studies have provided… CONTINUE READING
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