Arterial response to ketanserin and aspirin in patients with advanced peripheral atherosclerosis.


BACKGROUND In advanced atherosclerosis, endothelial lesions and turbulent flow in stenotic vessels result in platelet aggregation with the liberation of vasoactive factors, including thromboxane A2 and serotonin. This study was designed to assess the combined effect of these factors on arterial dimensions at the time of limb angiography in patients with… (More)


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