Arterial Oxygenation Determines Autoregulation of Cerebral Blood Flow in the Fetal Lamb

@article{Tweed1983ArterialOD,
  title={Arterial Oxygenation Determines Autoregulation of Cerebral Blood Flow in the Fetal Lamb},
  author={William A. Tweed and Jacques C{\^o}t{\'e} and Michael Pash and Hans Olav Christensen Lou},
  journal={Pediatric Research},
  year={1983},
  volume={17},
  pages={246-249}
}
Summary: We examined autoregulation of cerebral blood flow (CBF) over the range of oxygen tension commonly observed in the chronic fetal lamb preparation. Seventeen animals were surgically prepared under general anesthesia for chronic in utero studies. Based on measured resting arterial Po2 and calculated % saturation 24–48 h after surgery, two groups were defined: a normoxic group of eight with saturation of 57% or higher (our laboratory normal for physiologically stable preparations) and an… CONTINUE READING
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Autoregulation of Cerebral Blood Flow in the Preterm Fetal Lamb

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CITES BACKGROUND
HIGHLY INFLUENCED

Fetal cerebrovascular response to chronic hypoxia--implications for the prevention of brain damage.

  • The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
  • 2006
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CITES BACKGROUND

Cerebral O2 Supply Thresholds for the Preservation of Electrocortical Brain Activity During Hypotension in Near-Term-Born Lambs

Sandra van Os, Djien Liem, Jeroen Hopman, John Klaessens, Margot van de Bor
  • Pediatric Research
  • 2005

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