Arterial Oxygenation Determines Autoregulation of Cerebral Blood Flow in the Fetal Lamb

@article{Tweed1983ArterialOD,
  title={Arterial Oxygenation Determines Autoregulation of Cerebral Blood Flow in the Fetal Lamb},
  author={William A. Tweed and Jacques C{\^o}t{\'e} and Michael Pash and Hans Olav Christensen Lou},
  journal={Pediatric Research},
  year={1983},
  volume={17},
  pages={246-249}
}
Summary: We examined autoregulation of cerebral blood flow (CBF) over the range of oxygen tension commonly observed in the chronic fetal lamb preparation. Seventeen animals were surgically prepared under general anesthesia for chronic in utero studies. Based on measured resting arterial Po2 and calculated % saturation 24–48 h after surgery, two groups were defined: a normoxic group of eight with saturation of 57% or higher (our laboratory normal for physiologically stable preparations) and an… CONTINUE READING
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