Artemin growth factor increases nicotinic cholinergic receptor subunit expression and activity in nociceptive sensory neurons

@inproceedings{Albers2014ArteminGF,
  title={Artemin growth factor increases nicotinic cholinergic receptor subunit expression and activity in nociceptive sensory neurons},
  author={Kathryn M Albers and Xiu-lin Zhang and Charlotte M Diges and Erica S. Schwartz and Charles Inshik Yang and Brian M. Davis and Michael S Gold},
  booktitle={Molecular pain},
  year={2014}
}
BACKGROUND Artemin (Artn), a member of the glial cell line-derived growth factor (GDNF) family, supports the development and function of a subpopulation of peptidergic, TRPV1-positive sensory neurons. Artn (enovin, neublastin) is elevated in inflamed tissue and its injection in skin causes transient thermal hyperalgesia. A genome wide expression analysis of trigeminal ganglia of mice that overexpress Artn in the skin (ART-OE mice) showed elevation in nicotinic acetylcholine receptor (nAChR… CONTINUE READING
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A randomized, blinded, placebo-controlled, multiple ascending dose study of the safety, pharmacokinetics, and efficacy of neublastin in subjects with sciatica

  • P Okkerse, J Hay, +4 authors E Aycardi
  • 2013
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