Artemether-lumefantrine for the treatment of multidrug-resistant falciparum malaria.

  title={Artemether-lumefantrine for the treatment of multidrug-resistant falciparum malaria.},
  author={Mich{\`e}le van Vugt and Sornchai Looareesuwan and Polrat Wilairatana and Rose McGready and Leopoldo Villegas and Insa Gathmann and Rebecca Mull and Alan Brockman and Nicholas J White and François H Nosten},
  journal={Transactions of the Royal Society of Tropical Medicine and Hygiene},
  volume={94 5},
The efficacy and safety of the 6-dose regimen of artemether-lumefantrine were assessed in an open randomized trial in children and adults presenting with acute, uncomplicated Plasmodium falciparum malaria in Thailand between November 1997 and March 1998. 200 patients were enrolled in 2 centres: 150 received artemether-lumefantrine (i.e., a median total dose of 9.6 mg/kg [interquartile range 8.7-10.7] and 57.9 mg/kg of lumefantrine [52.4-64.0]) and 50 the standard combination of artesunate (12… CONTINUE READING

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