Arsenic trioxide alleviates airway hyperresponsiveness and eosinophilia in a murine model of asthma

@article{Chu2010ArsenicTA,
  title={Arsenic trioxide alleviates airway hyperresponsiveness and eosinophilia in a murine model of asthma},
  author={Kuan-Hua Chu and Chen-Chen Lee and Shao-Chi Hsin and Bao-chang Cai and Jin-hong Wang and Bor-Luen Chiang},
  journal={Cellular and Molecular Immunology},
  year={2010},
  volume={7},
  pages={375-380}
}
Asthma is one of the most common chronic airway inflammatory diseases. The clinical hallmarks of asthma include elevated serum levels of immunoglobulin E (IgE), eosinophilic inflammation and airway hyper-responsiveness (AHR). Arsenic trioxide (As2O3) is considered a carcinogen; however, it has also been used to treat diseases, such as syphilis, in traditional Chinese and Western medicine. Today, As2O3 is used as one of the standard therapies for acute promyelocytic leukemia (APL). Previous… CONTINUE READING
6 Citations
26 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 26 references

T celldependent regulation of eotaxin in antigeninduced pulmonary eosinophilia

  • JA MacLean, R Wenbey, AD Luster
  • Toxicol Sci
  • 2004

The role of eosinophils in the pathogenesis of asthma

  • AB Kay
  • Cytokine
  • 2002

Similar Papers

Loading similar papers…