Arsenic trioxide alleviates airway hyperresponsiveness and eosinophilia in a murine model of asthma

@article{Chu2010ArsenicTA,
  title={Arsenic trioxide alleviates airway hyperresponsiveness and eosinophilia in a murine model of asthma},
  author={Kuan-Hua Chu and Chen-Chen Lee and S. Hsin and Bao-chang Cai and J. Wang and B. Chiang},
  journal={Cellular and Molecular Immunology},
  year={2010},
  volume={7},
  pages={375-380}
}
  • Kuan-Hua Chu, Chen-Chen Lee, +3 authors B. Chiang
  • Published 2010
  • Medicine
  • Cellular and Molecular Immunology
  • Asthma is one of the most common chronic airway inflammatory diseases. The clinical hallmarks of asthma include elevated serum levels of immunoglobulin E (IgE), eosinophilic inflammation and airway hyper-responsiveness (AHR). Arsenic trioxide (As2O3) is considered a carcinogen; however, it has also been used to treat diseases, such as syphilis, in traditional Chinese and Western medicine. Today, As2O3 is used as one of the standard therapies for acute promyelocytic leukemia (APL). Previous… CONTINUE READING
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