Arsenic species, AS3MT amount, and AS3MT gene expression in different brain regions of mouse exposed to arsenite.

@article{SnchezPea2010ArsenicSA,
  title={Arsenic species, AS3MT amount, and AS3MT gene expression in different brain regions of mouse exposed to arsenite.},
  author={Luz Carmen S{\'a}nchez-Pe{\~n}a and Pavel Petrosyan and Mariana Ruiz Morales and N. Bello Gonz{\'a}lez and Gabriel Guti{\'e}rrez-Ospina and Luz Mar{\'i}a Del Razo and Mar{\'i}a E Gonsebatt},
  journal={Environmental research},
  year={2010},
  volume={110 5},
  pages={428-34}
}
Human exposure to inorganic arsenic (iAs) has been associated with cancer and serious injury to various internal organs, as well as peripheral neuropathy, endocrine disruption and diverse effects in the central nervous system (CNS). Using rodent models, it is possible to demonstrate As accumulation in the brain that leads to defects in operant learning, behavioral changes, and affect pituitary gonadotrophins. iAs biomethylation in the CNS is a significant process, yielding products that are… CONTINUE READING
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