Arsenic metabolism, genetic susceptibility, and risk of premalignant skin lesions in Bangladesh.

@article{Ahsan2007ArsenicMG,
  title={Arsenic metabolism, genetic susceptibility, and risk of premalignant skin lesions in Bangladesh.},
  author={Habibul Ahsan and Yu Chen and Muhammad G Kibriya and Vesna N Slavkovich and Faruque Parvez and Farzana Jasmine and M. Gamble and Joseph H. Graziano},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={2007},
  volume={16 6},
  pages={1270-8}
}
We conducted a case-control study to investigate interindividual variability in susceptibility to health effects of inorganic arsenic due to arsenic metabolism efficiency, genetic factors, and their interaction. A total of 594 cases of arsenic-induced skin lesions and 1,041 controls was selected from baseline participants in a large prospective cohort study in Bangladesh. Adjusted odds ratios (OR) for skin lesions were estimated in relation to the polymorphisms in the glutathione S-transferase… CONTINUE READING