Arsenic intoxication presenting with macrocytosis and peripheral neuropathy, without anemia.

@article{Heaven1994ArsenicIP,
  title={Arsenic intoxication presenting with macrocytosis and peripheral neuropathy, without anemia.},
  author={Ralph Heaven and Mary Duncan and Svetislava J. Vukelja},
  journal={Acta haematologica},
  year={1994},
  volume={92 3},
  pages={142-3}
}
A case of arsenic intoxication associated with macrocytosis and neuropathy, without anemia, is presented. Evaluation of a 68-year-old man with a long history of peripheral neuropathy and persistent macrocytosis revealed exposure to an insecticide. Analysis of urine and hair revealed elevated levels of arsenic. A short course of d-penicillamine failed to promote urinary excretion of arsenic. Removal of the insecticide resulted in resolution of macrocytosis and slight improvement of neuropathy… CONTINUE READING