Arsenic dose in patients with cutaneous carcinomata and hepatic haemangio-endothelioma after environmental and occupational exposure

@article{Zaldvar2004ArsenicDI,
  title={Arsenic dose in patients with cutaneous carcinomata and hepatic haemangio-endothelioma after environmental and occupational exposure},
  author={R. Zald{\'i}var and L. Prun{\'e}s and G. L. Ghai},
  journal={Archives of Toxicology},
  year={2004},
  volume={47},
  pages={145-154}
}
A total of 16 male cases with malignant tumours associated with arsenic-polluted water were observed in Tarapacá and Antofagasta Provinces, northern Chile. Fifteen of them had skin carcinomata and the remaining one a haemangio-endothelioma of liver. The 15 skin cancer cases had latent periods ranging from 12–45 years. Three patients were studied in detail. The first one (skin cancer) had a latent period of 20 years with a weighted mean dose of 1.2 mg/day (total dose for latent period 8.4 g… Expand
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