Arsenic and respiratory cancer in man: an occupational study.

  title={Arsenic and respiratory cancer in man: an occupational study.},
  author={Alice M Lee and Joseph F. Jr. Fraumeni},
  journal={Journal of the National Cancer Institute},
  volume={42 6},
To clarify the role of arsenic in human carcinogenesis, the mortality experience of 8,047 white male smelter workers exposed to arsenic trioxide during 1938-63 was studied and compared with that of the white male population of the same States. Smelter workers had an excess total mortality, due mainly to malignant neoplasms of the respiratory system and diseases of the heart. The threefold increase in respiratory cancer was analyzed in relation to the length of employment and degree of exposure… CONTINUE READING
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