Arsenic and atherosclerosis.

  title={Arsenic and atherosclerosis.},
  author={Petia Simeonova and Michael I. Luster},
  journal={Toxicology and applied pharmacology},
  volume={198 3},
Epidemiological studies have demonstrated a correlation between environmental or occupational arsenic exposure and a risk of vascular diseases related to atherosclerosis. Studies summarized in this review suggest that arsenic induces endothelial dysfunction, including inflammatory and coagulating activity as well as impairs nitric oxide (NO) balance. This may provide the pathophysiological basis for atherogenic potential of arsenic. Consistent with these data, arsenic accelerates… CONTINUE READING

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