Ars2 Regulates Both miRNA- and siRNA- Dependent Silencing and Suppresses RNA Virus Infection in Drosophila

Abstract

Intrinsic immune responses autonomously inhibit viral replication and spread. One pathway that restricts viral infection in plants and insects is RNA interference (RNAi), which targets and degrades viral RNA to limit infection. To identify additional genes involved in intrinsic antiviral immunity, we screened Drosophila cells for modulators of viral… (More)
DOI: 10.1016/j.cell.2009.04.045

Topics

7 Figures and Tables

Cite this paper

@article{Sabin2009Ars2RB, title={Ars2 Regulates Both miRNA- and siRNA- Dependent Silencing and Suppresses RNA Virus Infection in Drosophila}, author={Leah R. Sabin and Rui Zhou and Joshua J. Gruber and Nina Lukinova and Shelly A Bambina and Allison Berman and Chi-kong Lau and Craig B Thompson and Sara R. Cherry}, journal={Cell}, year={2009}, volume={138}, pages={340-351} }