Arrhythmogenic Phenotype in Dilated Cardiomyopathy: Natural History and Predictors of Life-Threatening Arrhythmias.

  title={Arrhythmogenic Phenotype in Dilated Cardiomyopathy: Natural History and Predictors of Life-Threatening Arrhythmias.},
  author={Anita Spezzacatene and Gianfranco Sinagra and M. Merlo and Giulia Barbati and Sharon L. Graw and Francesca Brun and Dobromir Slavov and Andrea di Lenarda and Ernesto Salcedo and Jeffrey Allen Towbin and Jeffrey E. Saffitz and Frank I. Marcus and Wojciech Zareba and Matthew R. G. Taylor and Luisa Mestroni},
  journal={Journal of the American Heart Association},
  volume={4 10},
BACKGROUND Patients with dilated cardiomyopathy (DCM) may present with ventricular arrhythmias early in the disease course, unrelated to the severity of left ventricular dysfunction. These patients may be classified as having an arrhythmogenic DCM (AR-DCM). We investigated the phenotype and natural history of patients with AR-DCM. METHODS AND RESULTS Two hundred eighty-five patients with a recent diagnosis of DCM (median duration of the disease 1 month, range 0 to 7 months) and who had Holter… CONTINUE READING


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