Arrestin translocation is induced at a critical threshold of visual signaling and is superstoichiometric to bleached rhodopsin.

@article{Strissel2006ArrestinTI,
  title={Arrestin translocation is induced at a critical threshold of visual signaling and is superstoichiometric to bleached rhodopsin.},
  author={Katherine J. Strissel and Maxim Sokolov and Lynn H Trieu and Vadim Y Arshavsky},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2006},
  volume={26 4},
  pages={1146-53}
}
Light induces massive translocation of major signaling proteins between the subcellular compartments of photoreceptors. Among them is visual arrestin responsible for quenching photoactivated rhodopsin, which moves into photoreceptor outer segments during illumination. Here, for the first time, we determined the light dependency of arrestin translocation, which revealed two key features of this phenomenon. First, arrestin translocation is triggered when the light intensity approaches a critical… CONTINUE READING
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