Arrestin Translocation Is Stoichiometric to Rhodopsin Isomerization and Accelerated by Phototransduction in Drosophila Photoreceptors

@article{Satoh2010ArrestinTI,
  title={Arrestin Translocation Is Stoichiometric to Rhodopsin Isomerization and Accelerated by Phototransduction in Drosophila Photoreceptors},
  author={Akiko K Satoh and Hongai Xia and Limin Yan and Che-Hsiung Liu and Roger C. Hardie and Donald F. Ready},
  journal={Neuron},
  year={2010},
  volume={67},
  pages={997-1008}
}
Upon illumination, visual arrestin translocates from photoreceptor cell bodies to rhodopsin and membrane-rich photosensory compartments, vertebrate outer segments or invertebrate rhabdomeres, where it quenches activated rhodopsin. Both the mechanism and function of arrestin translocation are unresolved and controversial. In dark-adapted photoreceptors of the fruitfly Drosophila, confocal immunocytochemistry shows arrestin (Arr2) associated with distributed photoreceptor endomembranes… CONTINUE READING

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