Arrested apoptosis of nurse cells during Hydra oogenesis and embryogenesis.

@article{Technau2003ArrestedAO,
  title={Arrested apoptosis of nurse cells during Hydra oogenesis and embryogenesis.},
  author={Ulrich Technau and Michael A Miller and Diane Bridge and Robert E. Steele},
  journal={Developmental biology},
  year={2003},
  volume={260 1},
  pages={191-206}
}
During Hydra oogenesis, an aggregate of germ cells differentiates into one oocyte and thousands of nurse cells. Nurse cells display a number of features typical of apoptotic cells and are phagocytosed by the growing oocyte. Yet, these cells remain unchanged in morphology and number until hatching of the polyp, which can occur up to 12 months later. Treatments with caspase inhibitors can block oocyte development during an early phase of oogenesis, but not after nurse cell phagocytosis has taken… CONTINUE READING