Arrest of transcription following anoxic exposure in a marine mollusc

@article{Larade2007ArrestOT,
  title={Arrest of transcription following anoxic exposure in a marine mollusc},
  author={Kevin Larade and Kenneth B. Storey},
  journal={Molecular and Cellular Biochemistry},
  year={2007},
  volume={303},
  pages={243-249}
}
The intertidal marine snail, Littorina littorea, is an anoxia tolerant species that endures long-term oxygen deprivation using a suite of compensatory metabolic adaptations that includes overall metabolic rate depression. Nuclear run-off assays were used to quantify the relative rates of mRNA transcription in nuclear extracts from hepatopancreas of aerobic and anoxic snails. Total [32P]-UTP incorporation into RNA by nuclei from 48 h anoxic snails ranged from 42 to 50% of that observed for… CONTINUE READING

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