Array comparative genomic hybridization of 18 pancreatic ductal adenocarcinomas and their autologous metastases

Abstract

Mortality rates of pancreatic cancer remain high, which is mainly due to advanced disease and metastasis. We hypothesized that genomic copy number alterations are enriched in metastatic cells compared to autologous primary tumors, which may inform on cancer-related pathways possibly serving as potential targets for specific therapies. We investigated 18… (More)
DOI: 10.1186/s13104-017-2886-0

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