Array CGH of fusion gene-positive leukemia-derived cell lines reveals cryptic regions of genomic gain and loss.

Abstract

Human leukemia-derived cell lines containing characteristic chromosomal translocations and inversions have been instrumental in identifying fusion genes implicated in the pathogenesis of the corresponding leukemia. Although chimeric fusion genes usually provide early and essential steps in the development of leukemia, they are not in themselves sufficient… (More)

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@article{Horsley2006ArrayCO, title={Array CGH of fusion gene-positive leukemia-derived cell lines reveals cryptic regions of genomic gain and loss.}, author={Sharon W. Horsley and Alan Mackay and Marjan Iravani and Kerry Fenwick and Haukur Valgeirsson and T. M. Dexter and Alan Ashworth and Lyndal Kearney}, journal={Genes, chromosomes & cancer}, year={2006}, volume={45 6}, pages={554-64} }