Array-CGH analysis of cell-free fetal DNA in 10 mL of amniotic fluid supernatant.


BACKGROUND Previously, we showed that analysis of amniotic fluid (AF) supernatant cell-free fetal (cff) DNA using DNA microarrays (array-CGH) allows for detection of whole chromosome differences between test and reference DNA. Subsequent technical advances have increased both the yield and quality of extracted cffDNA. Here we determined whether array-CGH… (More)


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