Arousal of a specific and persistent sodium appetite in the rat with continuous intracerebroventricular infusion of angiotensin II.

@article{Bryant1980ArousalOA,
  title={Arousal of a specific and persistent sodium appetite in the rat with continuous intracerebroventricular infusion of angiotensin II.},
  author={Robert W. Bryant and Alan N. Epstein and James Fitzsimons and Steven J. Fluharty},
  journal={The Journal of physiology},
  year={1980},
  volume={301},
  pages={365-82}
}
1. Prolonged exposure of the brain of the normal Na-replete rat to angiotensin II produced a marked and persistent Na appetite. In a first series of experiments, short-term, repeated systemic injections of isoprenaline or renin (both of which raise circulating angiotensin levels), and repeated intracranial injections of angiotensin II evoked increased ingestion of 2 . 7% NaCl. In the second series of experiments, continuous infusions of angiotensin II directly into the brain evoked extremely… CONTINUE READING

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