Aromatic naphthenic acids in oil sands process-affected water, resolved by GCxGC-MS, only weakly induce the gene for vitellogenin production in zebrafish (Danio rerio) larvae.

@article{Reinardy2013AromaticNA,
  title={Aromatic naphthenic acids in oil sands process-affected water, resolved by GCxGC-MS, only weakly induce the gene for vitellogenin production in zebrafish (Danio rerio) larvae.},
  author={H C Reinardy and Alan G. Scarlett and Theodore Burdick Henry and Charles Edward West and Lauren. Hewitt and Richard A. Frank and Steven J Rowland},
  journal={Environmental science & technology},
  year={2013},
  volume={47 12},
  pages={6614-20}
}
Process waters from oil sands industries (OSPW) have been reported to exhibit estrogenic effects. Although the compounds responsible are unknown, some aromatic naphthenic acids (NA) have been implicated. The present study was designed to investigate whether aromatic NA might cause such effects. Here we demonstrate induction of vitellogenin genes (vtg) in fish, which is a common bioassay used to indicate effects consistent with exposure to exogenous estrogens. Solutions in water of 20-2000 μg L… CONTINUE READING
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