Aromatic-aromatic interactions in the zinc finger motif. Analysis of the two-dimensional nuclear magnetic resonance structure of a mutant domain.

@article{Jasanoff1992AromaticaromaticII,
  title={Aromatic-aromatic interactions in the zinc finger motif. Analysis of the two-dimensional nuclear magnetic resonance structure of a mutant domain.},
  author={Alan Jasanoff and M Kochoyan and Ernest Fraenkel and Jonathan P. Lee and M. Angela Weiss},
  journal={Journal of molecular biology},
  year={1992},
  volume={225 4},
  pages={1035-47}
}
The folding and stability of globular proteins are determined by a variety of chemical mechanisms, including hydrogen bonds, salt bridges and the hydrophobic effect. Of particular interest are weakly polar interactions involving aromatic rings, which are proposed to regulate the geometry of closely packed protein interiors. Such interactions reflect the… CONTINUE READING