Aromatase inhibitors and cardiac toxicity: getting to the heart of the matter

@article{Gandhi2006AromataseIA,
  title={Aromatase inhibitors and cardiac toxicity: getting to the heart of the matter},
  author={Sonal Gandhi and Sunil Verma},
  journal={Breast Cancer Research and Treatment},
  year={2006},
  volume={106},
  pages={1-9}
}
Recent advances in breast cancer treatment include the advent of aromatase inhibitors (AIs) in the adjuvant setting with better efficacy and toxicity profiles than tamoxifen. However, AIs generally do not improve lipid profile as tamoxifen does, and there has been suggestion of increased cardiovascular risk with AI use. This has become an area of concern, particularly in light of the view that tamoxifen may protect against cardiovascular disease. This review of the current literature and… CONTINUE READING
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