Aromatase immunoreactivity in axon terminals of the vertebrate brain. An immunocytochemical study on quail, rat, monkey and human tissues.

@article{Naftolin1996AromataseII,
  title={Aromatase immunoreactivity in axon terminals of the vertebrate brain. An immunocytochemical study on quail, rat, monkey and human tissues.},
  author={Frederick Naftolin and Tam{\'a}s L. Horv{\'a}th and Robert L. Jakab and Csaba L{\'e}r{\'a}nth and Nobuhiro Harada and Jacques Balthazart},
  journal={Neuroendocrinology},
  year={1996},
  volume={63 2},
  pages={149-55}
}
Intraneuronal production of estradiol from testosterone has been shown to play a pivotal role in gender-specific brain development of most vertebrates, and to participate in numerous functions of the adult central nervous system. Previous biochemical and morphological approaches demonstrated that estrogen synthetase (aromatase) is present in specific limbic and hypothalamic structures. On the other hand, less attention has been paid to revealing its subcellular distribution. The possibility of… CONTINUE READING
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