Aromatase expression in Xenopus oocytes: a three cell-type model for the ovarian estradiol synthesis.

@article{Gohin2011AromataseEI,
  title={Aromatase expression in Xenopus oocytes: a three cell-type model for the ovarian estradiol synthesis.},
  author={Maella Gohin and Pascal Bodinier and Alexis Y. Fostier and Julien Bobe and Franck Chesnel},
  journal={Journal of molecular endocrinology},
  year={2011},
  volume={47 2},
  pages={241-50}
}
In contrast to the classical model describing the synthesis of androgens and estrogens as restricted to somatic cells, a previous study demonstrated that Xenopus laevis oocytes participate in androgen synthesis. The objective of our study was to determine whether Xenopus oocytes are also involved in estrogen synthesis. More precisely, we analyzed aromatase expression by in situ hybridization and RT-QPCR and measured aromatase activity. Aromatase, the enzyme responsible for estrogen synthesis… CONTINUE READING

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