Aroclor 1254-induced cytotoxicity in catecholaminergic CATH.a cells related to the inhibition of NO production.

@article{Kang2002Aroclor1C,
  title={Aroclor 1254-induced cytotoxicity in catecholaminergic CATH.a cells related to the inhibition of NO production.},
  author={Ju-Hee Kang and Wonhyung Jeong and Younjoo Park and Sung Yong Lee and Myeon Woo Chung and Hwa Kyung Lim and In Sook Park and Ki Hwan Choi and Soo Youn Chung and Dong Seop Kim and Chang Shin Park and Onyou Hwang and Joo il Kim},
  journal={Toxicology},
  year={2002},
  volume={177 2-3},
  pages={
          157-66
        }
}
The neuronal nitric oxide synthase (nNOS) specific inhibitor, 7-nitroindazole (7-NI), and the nitric oxide (NO) donor (S-nitroso-N-acetylpenicillarnine, SNAP) were used to study the role of NO in polychlorinated biphenyl (PCB: Aroclor 1254)-induced cytotoxicity in the immortalized dopaminergic cell line (CATH.a cells), derived from the central nervous system of mice. Treatment of the dopaminergic cells with various concentrations of Aroclor 1254 (0.5-10 microg/ml), a commercial PCB mixture… CONTINUE READING
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