Arm immobilization causes cortical plastic changes and locally decreases sleep slow wave activity

@article{Huber2006ArmIC,
  title={Arm immobilization causes cortical plastic changes and locally decreases sleep slow wave activity},
  author={Reto Huber and Marie Felice Ghilardi and Marcello Massimini and Fabio Ferrarelli and Brady Alexander Riedner and Michael J. Peterson and Giulio Tononi},
  journal={Nature Neuroscience},
  year={2006},
  volume={9},
  pages={1169-1176}
}
Sleep slow wave activity (SWA) is thought to reflect sleep need, increasing after wakefulness and decreasing after sleep. We showed recently that a learning task involving a circumscribed brain region produces a local increase in sleep SWA. We hypothesized that increases in cortical SWA reflect synaptic potentiation triggered by learning. To further investigate the link between synaptic plasticity and sleep, we asked whether a procedure leading to synaptic depression would cause instead a… CONTINUE READING
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