Aripiprazole relieves motivational anhedonia in rats.

Abstract

BACKGROUND Anhedonia is considered a relevant feature in depression and psychosis, characterized by poor treatment outcome, and associated with deficits in mesolimbic dopaminergic responsiveness. Clinical studies suggest the potential utility of aripiprazole as adjunctive therapy for resistant depression. Since aripiprazole can stabilize the dopaminergic… (More)
DOI: 10.1016/j.jad.2017.10.032

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