Aripiprazole for Tourette's syndrome: a systematic review and meta‐analysis

@article{Zheng2016AripiprazoleFT,
  title={Aripiprazole for Tourette's syndrome: a systematic review and meta‐analysis},
  author={Wei Zheng and Xian-Bin Li and Ying-qiang Xiang and Bao-Liang Zhong and Helen Fung Kum Chiu and Gabor S. Ungvari and Chee H. Ng and Grace K I Lok and Yutao Xiang},
  journal={Human Psychopharmacology: Clinical and Experimental},
  year={2016},
  volume={31},
  pages={11 - 18}
}
  • W. Zheng, Xian-Bin Li, Y. Xiang
  • Published 1 January 2016
  • Psychology, Medicine
  • Human Psychopharmacology: Clinical and Experimental
To review the efficacy and safety of aripiprazole (ARI) for Tourette's syndrome (TS). 

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References

SHOWING 1-10 OF 49 REFERENCES

A case series of patients with Tourette's syndrome in the United Kingdom treated with aripiprazole

These cases illustrate that a new neuroleptic, aripiprazole, may be an effective treatment for the motor and vocal tics of Tourette Syndrome (TS), even in younger people.

Topiramate for Tourette's syndrome in children: a meta-analysis.

Systemic review of aripiprazole for the treatment of children and adolescents with tic disorders.

Current evidence suggests that aripiprazole is effective for treating tic and Tourette disorders in both children and adolescents, and it seems that its adverse effect profile is safer than pimozide and some other antipsychotics.

Case series on the use of aripiprazole for Tourette syndrome.

A retrospective chart review of six youth with TS and comorbid obsessive–compulsive disorder (OCD) who were treated for 12 wk with aripiprazole shows value for treating neuropsychiatric disorders in children.

Treatment of Tourette's syndrome with haloperidol, review of 34 cases.

Most patients were able to achieve over 90% decrease in their symptoms after one year of treatment and Haloperidol was a difficult drug to use effectively.

A case of late-onset Tourette's disorder successfully treated with aripiprazole: View from blood levels of catecholamine metabolites and brain-derived neurotrophic factor (BDNF)

The present case suggests that aripiprazole might ameliorate tics and emotional instability via influencing dopaminergic neurons in late-onset TD.

Aripiprazole for the Treatment of Tourette Syndrome: A Case Series of 100 Patients

The results corroborate previous data suggesting that aripiprazole is effective and safe in most patients and clarify that beneficial effects sustain and confirm effectiveness in adult patients.

[A multicenter controlled study on aripiprazole treatment for children with Tourette syndrome in China].

Aripiprazole was safe and well tolerated in Chinese population, and can be considered as a new valid option for the treatment of tic disorders.

Aripiprazole in children and adolescents with Tourette's disorder: an open-label safety and tolerability study.

Aripiprazole appears to be a safe and tolerable treatment in children and adolescents with TD that appears to reduce tics; it should be further investigated as a treatment option in controlled trials.

Acute Dystonia with Low-Dosage Aripiprazole in Tourette's Disorder

This is the first report concerning an aripiprazole-induced dystonic episode in an adult, and it is especially notable because it occurred at low dosage.