Argyrophilic grain disease: a late-onset dementia with distinctive features among tauopathies.

@article{Tolnay2004ArgyrophilicGD,
  title={Argyrophilic grain disease: a late-onset dementia with distinctive features among tauopathies.},
  author={Markus Tolnay and Florence Clavaguera},
  journal={Neuropathology : official journal of the Japanese Society of Neuropathology},
  year={2004},
  volume={24 4},
  pages={
          269-83
        }
}
Argyrophilic grain disease (AgD) is a late-onset dementia morphologically characterized by the presence of abundant spindle-shaped argyrophilic grains (ArG) in neuronal processes and coiled bodies in oligodendrocytes. AgD changes consist of the microtubule-associated protein tau in an abnormally and hyperphosphorylated state and are mainly found in limbic regions, for example, in the hippocampus, the entorhinal and transentorhinal cortices and the amygdala. AgD shows a significant correlation… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 47 CITATIONS

Similar Papers

Loading similar papers…