Arginine vasopressin mediates cardiovascular responses to hypoxemia in fetal sheep.

@article{Perez1989ArginineVM,
  title={Arginine vasopressin mediates cardiovascular responses to hypoxemia in fetal sheep.},
  author={R. Tamayo Perez and Mauricio Espinoza and Raquel Riquelme and Julian T. Parer and A J Llanos},
  journal={The American journal of physiology},
  year={1989},
  volume={256 5 Pt 2},
  pages={R1011-8}
}
Acute hypoxemia results in hypertension, bradycardia, and cardiac output redistribution in fetal sheep. The blood flow redistribution is produced by differential changes in vascular resistance of various fetal organs. alpha-Adrenergic activity is one of the few vasoconstrictor mechanisms thus far identified in the hypoxemic fetal sheep. Arginine vasopressin (AVP) is a potent vasoconstrictor in adults. Since AVP administration to the normoxic fetus mimics some of the fetal cardiovascular… CONTINUE READING

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