Arginine stimulates growth hormone secretion by suppressing endogenous somatostatin secretion.

@article{AlbaRoth1988ArginineSG,
  title={Arginine stimulates growth hormone secretion by suppressing endogenous somatostatin secretion.},
  author={J. Alba-Roth and O. M{\"u}ller and J. Schopohl and K. von Werder},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1988},
  volume={67 6},
  pages={
          1186-9
        }
}
  • J. Alba-Roth, O. Müller, +1 author K. von Werder
  • Published 1988
  • Medicine
  • The Journal of clinical endocrinology and metabolism
  • To determine how arginine (Arg) stimulates GH secretion, we investigated its interaction with GHRH in vivo and in vitro. Six normal men were studied on four occasions: 1) Arg-TRH, 30 g arginine were administered in 500 mL saline in 30 min, followed by an injection of 200 micrograms TRH; 2) GHRH-Arg-TRH, 100 micrograms GHRH-(1-44) were given iv as a bolus immediately before the Arg infusion, followed by 200 micrograms TRH, iv; 3) GHRH test, 100 micrograms GHRH were given as an iv bolus; and 4… CONTINUE READING
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