Arginine-specific reagents remove sodium channel inactivation

@article{Eaton1978ArgininespecificRR,
  title={Arginine-specific reagents remove sodium channel inactivation},
  author={Douglas C. Eaton and Malcolm S. Brodwick and Gerry Stephen Oxford and Bernardo Rudy},
  journal={Nature},
  year={1978},
  volume={271},
  pages={473-476}
}
PROTEINS are often suggested to be the molecular components of excitable membranes which confer voltage-dependent permeability properties on nerve and muscle cells. Because of the relatively low concentration of the protein molecules directly responsible for ionic conductances compared with other membrane components, the isolation, characterisation, and reconstitution of these proteins is still at a rather early stage. Certain aspects of the molecular nature of the conductance mechanisms of… CONTINUE READING

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