Arginine reduces bacterial invasion in rats with head injury: an in vivo evaluation by bioluminescence.

@article{Moinard2012ArginineRB,
  title={Arginine reduces bacterial invasion in rats with head injury: an in vivo evaluation by bioluminescence.},
  author={Christophe Moinard and Saber David Barbar and Caroline Choisy and M. -J. Butel and Michel Francis Bureau and Michel Hasselmann and Luc A Cynober and Christine A. Charrueau},
  journal={Critical care medicine},
  year={2012},
  volume={40 1},
  pages={278-80}
}
OBJECTIVES The benefit of arginine in intensive care unit patients with severe sepsis is still controversial. An excessive supply of arginine could lead to an overproduction of nitric oxide and could be responsible for septic shock and multiorgan failure. However, this claim is not supported by any experimental or clinical data. We set out to determine whether an enteral supply of arginine would modulate bacterial invasion in rats with head injury. METHODS Male Sprague-Dawley rats with head… CONTINUE READING