Arginase Promotes Endothelial Dysfunction and Hypertension in Obese Rats


OBJECTIVE This study investigated whether arginase contributes to endothelial dysfunction and hypertension in obese rats. METHODS Endothelial function and arginase expression were examined in skeletal muscle arterioles from lean and obese Zucker rats (ZRs). Arginase activity, arginine bioavailability, and blood pressure were measured in lean and obese… (More)
DOI: 10.1002/oby.20969


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