ArgR of Streptomyces coelicolor Is a Pleiotropic Transcriptional Regulator: Effect on the Transcriptome, Antibiotic Production, and Differentiation in Liquid Cultures

@inproceedings{Botas2018ArgROS,
  title={ArgR of Streptomyces coelicolor Is a Pleiotropic Transcriptional Regulator: Effect on the Transcriptome, Antibiotic Production, and Differentiation in Liquid Cultures},
  author={Alma Botas and Rosario P{\'e}rez-Redondo and Antonio Rodr{\'i}guez-Garc{\'i}a and Rub{\'e}n {\'A}lvarez-{\'A}lvarez and Paula Yag{\"u}e and Angel Manteca and Paloma Liras},
  booktitle={Front. Microbiol.},
  year={2018}
}
ArgR is a well-characterized transcriptional repressor controlling the expression of arginine and pyrimidine biosynthetic genes in bacteria. In this work, the biological role of Streptomyces coelicolor ArgR was analyzed by comparing the transcriptomes of S. coelicolor ΔargR and its parental strain, S. coelicolor M145, at five different times over a 66-h… CONTINUE READING