ArgR is an essential local transcriptional regulator of the arcABC operon in Streptococcus suis and is crucial for biological fitness in an acidic environment.

@article{Fulde2011ArgRIA,
  title={ArgR is an essential local transcriptional regulator of the arcABC operon in Streptococcus suis and is crucial for biological fitness in an acidic environment.},
  author={Marcus Fulde and Joerg Willenborg and Astrid de Greeff and Laurentiu Benga and Hilde E. Smith and Peter Valentin-Weigand and Ralph Goethe},
  journal={Microbiology},
  year={2011},
  volume={157 Pt 2},
  pages={572-82}
}
Streptococcus suis is one of the most important pathogens in pigs and can also cause severe infections in humans. Despite its clinical relevance, very little is known about the factors that contribute to its virulence. Recently, we identified a new putative virulence factor in S. suis, the arginine deiminase system (ADS), an arginine catabolic enzyme system encoded by the arcABC operon, which enables S. suis to survive in an acidic environment. In this study, we focused on ArgR, an ADS… CONTINUE READING

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