Arecoline suppresses HaCaT cell proliferation through cell cycle regulatory molecules.

@article{Zhou2013ArecolineSH,
  title={Arecoline suppresses HaCaT cell proliferation through cell cycle regulatory molecules.},
  author={Zhong-Su Zhou and Ming Li and Feng Gao and Jie-ying Peng and Hai-bo Xiao and Li-Xia Dai and Shi-Rong Lin and Rui Zhang and Long-yu Jin},
  journal={Oncology reports},
  year={2013},
  volume={29 6},
  pages={2438-44}
}
Betel nut chewing is the most common cause of oral submucous fibrosis (OSF). Arecoline is the main component of the betel nut, and is associated with the occurrence and development of OSF through cytotoxicity, genotoxicity and DNA damage. Similar types of stimuli elicit differential responses in different cells. In the present study, we investigated the… CONTINUE READING